Peer-Reviewed Articles
2018
Zhou W, Woodson M, Neupane B, Bai F, Sherman MB, Choi KH, Neelakanta G, Sultana H. Exosomes serve as novel modes of tick-borne flavivirus transmission from arthropod to human cells and facilitates dissemination of viral RNA and proteins to the vertebrate neuronal cells. PLoS pathogens. 2018;14(1):e1006764. Epub 2018/01/05. doi: 10.1371/journal.ppat.1006764. PubMed PMID: 29300779. PLoS pathogens featured article, highlighted as research news in EurekAlert
2017
Taank V, Dutta S, Dasgupta A, Steeves TK, Fish D, Anderson JF, Sultana H and Neelakanta G #. (2017). Human rickettsial pathogen modulates arthropod organic anion transporting polypeptide and tryptophan pathway for its survival in ticks. Scientific Reports (Nature press), Oct 16;7(1):13256.# Corresponding author
Dutta S, Huddleston A, Khanal S, Simms C, Arca JF, Mitra A, Heller L, Kraj PJ, Ledizet M, Anderson JF, Neelakanta G, Holder AA and Sultana H. Coordination of different complexes to copper(II) and cobalt(III) metal centers enhances Zika virus and dengue virus loads in both arthropod cells and human keratinocytes. Biochim Biophys Acta. 2017 Oct 10. pii: S0304-4165(17)30325-2. doi: 10.1016/j.bbagen.2017.10.004.
Khanal S, Sultana H, Catravas JD, Carlyon JA, Neelakanta G # (2017) Anaplasma phagocytophilum infection modulates expression of megakaryocyte cell cycle genes through phosphatidylinositol-3-kinase signaling. PloS one ;12(8):e0182898. Epub 2017/08/11. # Corresponding author
Neelakanta G #, Sultana H, Sonenshine DE and Andersen JF. Identification and characterization of a histamine-binding lipocalin-like molecule from the relapsing fever tick Ornithodoros turicata. Insect Mol. Bio. 2017 Nov 22. doi: 10.1111/imb.12362 # Corresponding author
Neelakanta, G $., Sultana, H., Sonenshine, D.E., and Marconi, R.T. (2017). An In Vitro Blood-Feeding Method Revealed Differential Borrelia turicatae (Spirochaetales: Spirochaetaceae) Gene Expression After Spirochete Acquisition and Colonization in the Soft Tick Ornithodoros turicata (Acari: Argasidae). J Med Entomol 54, 441-449. $ Corresponding author
Vora, A., Taank, V., Dutta, S.M., Anderson, J.F., Fish, D., Sonenshine, D.E., Catravas, J.D., Sultana, H., and Neelakanta, G.$ (2017). Ticks elicit variable fibrinogenolytic activities upon feeding on hosts with different immune backgrounds. Scientific reports 7, 44593. $ Corresponding author
2016
Sultana H, Patel U, Toliver M, Maggi RG, Neelakanta G $ (2016) Molecular identification and bioinformatics analysis of a potential anti-vector vaccine candidate, 15-kDa salivary gland protein (Salp15), from Ixodes affinis ticks. Ticks Tick Borne Dis 7: 46-53. $ Corresponding author
Neelakanta G $, Sultana H $ (2016) Viral receptors of the gut: vector-borne viruses of medical importance. Curr Opin Insect Sci 16: 44-50. $ Corresponding authors, † invited work
2015
Sultana H, Patel U, Sonenshine DE, Neelakanta G $ (2015) Identification and comparative analysis of subolesin/akirin ortholog from Ornithodoros turicata ticks. Parasit Vectors 8: 132. $ Corresponding author
Neelakanta G $, Sultana H $ (2015) Transmission-Blocking Vaccines: Focus on Anti-Vector Vaccines against Tick-Borne Diseases. Arch Immunol Ther Exp (Warsz) 63: 169-179. $ Corresponding authors, † invited work
Heisig M, Mattessich S, Rembisz A, Acar A, Shapiro M, Booth CJ, Neelakanta G, Fikrig E (2015) Frostbite protection in mice expressing an antifreeze glycoprotein. PLoS One 10: e0116562.
2014
Heisig M, Abraham NM, Liu L, Neelakanta G $, Mattessich S, Sultana H et al. (2014) Antivirulence properties of an antifreeze protein. Cell Rep 9: 417-424. $ Equal-first authors
2013
Yang X, Hegde S, Shroder DY, Smith AA, Promnares K, Neelakanta G, Anderson JF, Fikrig E, Pal U (2013) The lipoprotein La7 contributes to Borrelia burgdorferi persistence in ticks and their transmission to naive hosts. Microbes Infect 15: 729-737.
Neelakanta G, Sultana H (2013) The use of metagenomic approaches to analyze changes in microbial communities. Microbiol Insights 6: 37-48. † invited work
2012
Neelakanta G, Hudson AM, Sultana H, Cooley L, Fikrig E (2012) Expression of Ixodes scapularis antifreeze glycoprotein enhances cold tolerance in Drosophila melanogaster. PLoS One 7: e33447.
Sultana H, Neelakanta G, Rivero F, Blau-Wasser R, Schleicher M, et al. (2012) Ectopic expression of cyclase associated protein CAP restores the streaming and aggregation defects of adenylyl cyclase a deficient Dictyostelium discoideum cells. BMC Dev Biol 12: 3.
Sultana H, Neelakanta G, Foellmer HG, Montgomery RR, Anderson JF, et al. (2012) Semaphorin 7A contributes to West Nile virus pathogenesis through TGF-beta1/Smad6 signaling. J Immunol 189: 3150-3158.
Ouyang Z, Narasimhan S, Neelakanta G, Kumar M, Pal U, et al. (2012) Activation of the RpoN-RpoS regulatory pathway during the enzootic life cycle of Borrelia burgdorferi. BMC Microbiol 12: 44.
2010
Neelakanta G, Sultana H, Fish D, Anderson JF, Fikrig E (2010) Anaplasma phagocytophilum induces Ixodes scapularis ticks to express an antifreeze glycoprotein gene that enhances their survival in the cold. J Clin Invest 120: 3179-3190. Selected as a "Science editor choice article"
Sultana H, Neelakanta G $, Kantor FS, Malawista SE, Fish D, et al. (2010) Anaplasma phagocytophilum induces actin phosphorylation to selectively regulate gene transcription in Ixodes scapularis ticks. J Exp Med 207: 1727-1743. $ Equal-first author
2009
Sultana H, Neelakanta G, Eichinger L, Rivero F, Noegel AA (2009) Microarray phenotyping places cyclase associated protein CAP at the crossroad of signaling pathways reorganizing the actin cytoskeleton in Dictyostelium. Exp Cell Res 315: 127-140.
Sultana H, Foellmer HG, Neelakanta G, Oliphant T, Engle M, et al. (2009) Fusion loop peptide of the West Nile virus envelope protein is essential for pathogenesis and is recognized by a therapeutic cross-reactive human monoclonal antibody. J Immunol 183: 650-660.
Sankar TS, Neelakanta G, Sangal V, Plum G, Achtman M, et al. (2009) Fate of the H-NS-repressed bgl operon in evolution of Escherichia coli. PLoS Genet 5: e1000405.
Neelakanta G, Sankar TS, Schnetz K (2009) Characterization of a beta-glucoside operon (bgc) prevalent in septicemic and uropathogenic Escherichia coli strains. Appl Environ Microbiol 75: 2284-2293.
Fikrig E, Narasimhan S, Neelakanta G, Pal U, Chen M, et al. (2009) Toll-like receptors 1 and 2 heterodimers alter Borrelia burgdorferi gene expression in mice and ticks. J Infect Dis 200: 1331-1340.
2008
Pal U, Dai J, Li X, Neelakanta G, Luo P, et al. (2008) A differential role for BB0365 in the persistence of Borrelia burgdorferi in mice and ticks. J Infect Dis 197: 148-155.
2007
Neelakanta G, Li X, Pal U, Liu X, Beck DS, et al. (2007) Outer surface protein B is critical for Borrelia burgdorferi adherence and survival within Ixodes ticks. PLoS Pathog 3: e33.
Li X, Neelakanta G $, Liu X, Beck DS, Kantor FS, et al. (2007) Role of outer surface protein D in the Borrelia burgdorferi life cycle. Infect Immun 75: 4237-4244. ,$ Equal-first author
2002
Thomas AM, Neelakanta G, Mahadevan S, Nethaji M, Chakravarty AR (2002) Syntheses, crystal structure, and nuclease activity of oxalato-bridged dicopper(II) complexes with planar N-donor heterocyclic bases European Journal of Inorganic Chemistry, (10): 2720-2726.
Santra BK, Reddy PA, Neelakanta G, Mahadevan S, Nethaji M, et al. (2002) Oxidative cleavage of DNA by a dipyridoquinoxaline copper(II) complex in the presence of ascorbic acid. J Inorg Biochem 89: 191-196.
Book Chapters
2014
Sultana, H., and Neelakanta G. * 2014. Vector-borne diseases. In: Diseases and Theranostics, Biotechnology (multi-volume set), Ed: J.N.Govil, Studium Press LLC, U.S.A 9:241-270. * Corresponding author
Neelakanta G., and Sultana, H. 2014. Bacterial, Protozoan and Viral Life-Threatening Diseases. In: Diseases and Theranostics, Biotechnology (multi-volume set), Ed: J.N.Govil, Studium Press LLC, U.S.A 9:271-289.